Aging Brain Center Publications at the Institute for Aging Research (IFAR)

 Aging Brain Center (ABC) Publications

General

  1. Inouye SK.  Current concepts:  Delirium in older persons.  N Engl J Med 2006; 354: 1157-1165. 
  2. Inouye SK, Zhang Y, Han L, Leo-Summers L, Jones R, Marcantonio E.  Recoverable cognitive dysfunction at hospital admission in older persons during acute illness.  J Gen Intern Med 2006; 21: 1276-1281. 
  3. Inouye SK, Studenski S, Tinetti ME, Kuchel GA.  Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept.  J Am Geriatr Soc  2007;55: 780-791 (with editorial).
  4. Inouye SK, Zhang Y, Jones RN, Shi P, Cupples LA, Calderon HN, Marcantonio ER.  Risk factors for hospitalization among community-dwelling primary care older patients: development and validation of a predictive model.  Med Care  2008;46:726-731.  PubMed ID: PMC2516963
  5. Marcantonio EM, Aneja J, Jones RN, Alsop DC, Fong TG, Crosby GJ, Culley DJ, Cupples LA, Inouye SK.  Maximizing clinical research participation in frail older persons: identification of barriers and motivators.  J Am Geriatr Soc 2008; 56: 1522-1527. PMC18662204
  6. Yang FM, Inouye SK, Fearing MA, Kiely DK, Marcantonio ER, Jones RN.  Participation in activity and risk for incident delirium.  J Am Geriatr Soc. 2008;56:1479-1484. PubMed ID: PMC18547359 
  7. Fong TG, Jones RN, Shi P, Marcantonio ER, Yap L, Rudolph JL, Yang FM, Kiely DK, Inouye SK.  Delirium accelerates cognitive decline in Alzheimer's disease.  Neurology.  2009;72:1570-1575.   

The Interrelationship of Delirium and Dementia -
Special Series in Journal of Gerontology: Medical Sciences

  1. Inouye SK, Ferrucci L.  Elucidating the pathophysiology of delirium and the interrelationship of delirium and dementia.  J Gerontol Med Sci 2006;61A: 1277-1280. 
  2. Marcantonio ER, Rudolph JL, Culley D, Crosby G, Alsop D, Inouye SK.  Serum biomarkers for delirium. J Gerontol Med Sci 2006;61A: 1281-1286.
  3. Alsop DC, Fearing MA, Johnson K, Sperling R, Fong TG, Inouye SK.  The role of neuro-imaging in elucidating delirium pathophysiology.  J Gerontol Med Sci 2006;61A: 1287-1293.  
  4. Fong TG, Bogardus ST, Daftary A, Auerbach E, Blumenfled H, Modur S, Leo-Summers L, Seibyl J, Inouye SK.  Delirium and Dementia: Cerebral perfusion changes in older delirious patients using 99mTcHMPAO SPECT. J Gerontol Med Sci 2006;61A: 1294-1300. 
  5. Xie Z, Dong Y, Maeda, U, Moir R, Inouye SK, Culley DJ, Crosby G, Tanzi RE.  Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia.  J Gerontol Med Sci 2006;61A: 1300-1306.  
  6. Jones RN, Yang FM, Zhang Y, Kiely DK, Marcantonio ER, Inouye SK.  Does educational attainment contribute to risk for delirium? A potential role for cognitive reserve.  J Gerontol Med Sci 2006;61A: 1307-1311.

Recognition, Prediction and Outcomes of Delirium

  1. Leslie DL, Zhang Y, Holford TR, Bogardus ST, Leo-Summers LS, Inouye SK.  Premature death associated with delirium at one year follow-up.  Arch Intern Med  2005;165: 1657-62. 
  2. Inouye SK, Zhang Y, Jones RN, Kiely DK, Yang F, Marcantonio ER.  Risk factors for delirium at hospital discharge:  development and validation of a predictive model.  Arch Intern Med 2007;167: 1406-1413.  
  3. Leslie DL, Marcantonio ER, Zhang Y, Leo-Summers L, Inouye SK.  One-year health care costs associated with delirium in the elderly.  Arch Intern Med  2008;168: 27-32. 
  4. Hshieh TT, Fong TG, Marcantonio ER, Inouye SK.  Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence.  J Gerontol Med Sci  2008; 63A:M764-772.
  5. Wei LA, Fearing MA, Sternberg E, Inouye SK.  The Confusion Assessment Method (CAM): a systematic review of current usage.  J Am Geriatr Soc  2008;56: 823-830.
  6. Yang FM, Inouye SK, Fearing MA, Kiely DK, Marcantonio ER, Jones RN.  Participation in activity and risk for incident delirium.  J Am Geriatric Soc  2008;56: 1479-1484.
  7. Kiely DK, Marcantonio ER, Inouye SK, Shaffer ML, Bergmann MA, Yang FM, Fearing MA, Jones RN.  Persistent delirium predicts increased mortality.  J Am Geriatr Soc. 2009;57:55-61. 

Postoperative Cognitive Dysfunction (POCD)

  1. Rudolph JL, Jones RN, Rasmussen LS, Silverstein JH, Inouye SK, Marcantonio ER.  Independent vascular and cognitive risk factors for postoperative delirium.  Amer J Med 2007; 120: 807-813.
  2. Rudolph JL, Marcantonio ER, Culley DJ, Silverstein JH, Rasmussen LS, Crosby GJ, Inouye SK.  Delirium is associated with early postoperative cognitive dysfunction.  Anesthesia 2008; 63: 941-947.

The Hospital Elder Life Program

  1. Bradley EH, Webster TR, Baker D, Schlesinger M, Inouye SK.  After adoption:  Sustaining the innovation.  a case study of disseminating the Hospital Elder Life Program.  J Am Geriatr Soc 2005; 53: 1455-1461. 
  2. Leslie DL, Zhang Y, Bogardus ST, Holford TR, Leo-Summers L, Inouye SK.  Consequences of preventing delirium in hospitalized older adults on nursing home costs.  J Am Geriatr Soc  2005; 53: 405-9.
  3. Inouye, SK, Baker DI, Fugal P, Bradley EH.  Dissemination of the Hospital Elder Life Program: implementation, adaptation, and successes.  J Am Geriatr Soc 2006;54: 1492-1499. 
  4. Rubin FH, Williams JT, Lescisin DA, Mook WJ, Hassan S, Inouye SK.  Replicating the Hospital Elder Life Program (HELP) in a community hospital and demonstrating effectiveness using administrative data.  J Am Geriatr Soc  2006;54: 969-974. 
  5. Bradley EH, Webster TR, Schlesinger M, Baker DI, Inouye SK.  The roles of senior management in improving hospital experiences for frail older adults.  Journal of Healthcare Management 2006; 51: 323-337. 
  6. Bradley EH, Webster TR, Schlesinger M, Baker DI, Inouye SK.  Patterns of diffusion of evidence-based clinical programmes: a case study of the Hospital Elder Life Program.  BMJ-Qual Saf Health Care 2006; 15:a334-338.
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